Plasmon‐Induced Photopolymerization of Molecularly Imprinted Polymers for Nanosensor Applications

A new simple, fast, and versatile method is developed to functionalize gold nanoparticles (AuNPs) via nanoscale layers of molecularly imprinted polymers (MIPs). The key step based on near-field radical photopolymerization the MIP prepolymerization mixture. This enables fabrication [email protected] hybrid nanoparticles, which are used as substrates for localized surface plasmon resonance surface-enhanced Raman spectroscopy (SERS) analysis with excellent sensitivity specificity. To demonstrate performance protected], methylene blue-specific MIPs prepared. SERS detection in range 10 nm. Specificity demonstrated by comparing response a non-imprinted control polymer interference testing two analogs (Rhodamine 6G Rhodamine 110). allows obtain robust reusable sensor surfaces high selectivity. nanometric thickness shorter times (10 min), thereby improving MIP-based sensors opening up perspectives molecules at very low concentrations.